For you, it will require great discipline and work. A systematic review and meta-analysis of randomized controlled trials. Ashwagandha is a herb which can also be used to treat the symptoms associated with depression, anxiety and insomnia. I've spent a good 6 or 7 hours trying to figure out if ashwagandha and bacopa are safe with an SSRI, and my conclusion is that they are safe. You can use the study as a second opinion to make health care decisions. Dosage of drugs is not considered in the study. J R Coll Physicians Edinb. Drug interactions are reported among people who take Lexapro and Ashwagandha. "Peripheral edema occurring during treatment with risperidone combined with citalopram", Agitation (state of anxiety or nervous excitement), Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection), Akathisia (a movement disorder characterized by a feeling of inner restlessness), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Anhedonia (inability to experience pleasure from activities usually found enjoyable), Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires), Arthritis (form of joint disorder that involves inflammation of one or more joints), Atelectasis (partial or complete collapse of the lung), Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles), Bradycardia (abnormally slow heart action), Bronchitis (inflammation of the mucous membrane in the bronchial tubes), Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder), Cardio-respiratory arrest (sudden dysfunction of heart and lungs), Celiac disease - sprue (a disease of the small intestine), Cerebral haemorrhage (bleeding within the brain), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving), Completed suicide (act of taking one's own life), Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body), Coronary heart disease (narrowing or blockage of the coronary arteries), Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis), Dehydration (dryness resulting from the removal of water), Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. Its effects on arterial blood pressure in anaesthetized dogs. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Dosage of drugs is not considered in the study. Different individuals may respond to medication in different ways. View abstract. The concomitant use of ashwagandha and celexa might increase the chances of sedation. Rhodiola is an appreciable MAOI (in my experience) and might interact with Wellbutrin in a negative manner. Ashwagandha has anti-MAOI effects so i have no idea wether it would cancel Rhodiolas effects. Both herbs have a broad pharmacology so if you are to try them introduce seperately and slowly. The effect of total alkaloids on the smooth muscles. Ashwagandha contains a class compounds called withanolides, which may help reduce stress and inflammation while boosting immune system activity in the body. Bhattacharya SK, Satyan KS, Ghosal S. Antioxidant activity of glycowithanolides from Withania somnifera. Some of the possible side These meds are used to treat the symptoms of depression and anxiety by blocking serotonin transporters (SERT), which results in increased serotonin activity in your body. It's a stimulating adaptogen often used by athletes to allow them to work out longer. But ashwaghanda and bacopa are safe to take with an SSRI. Analgesics. Yakugaku Zasshi 2008;128(8):1159-1167. Celexa has active ingredients of citalopram hydrobromide. Bjrnsson HK, Bjrnsson ES, Avula B, et al. The other stuff might be useful, but for other things, and again, apple cider vinegar has to be the right form (organically grown with the mother) to do anything and some people do not do well with the acid. Indian J Exp Biol 2000;38:607-9. It is best to ask for your doctors approval before using any medication or any other substance that possess medicinal properties, with your antidepressant. The supplements that looked like they helped the most were: This analysis also identified single studies that were encouraging for creatine. You may think that these supplements are safe because they also have antidepressant effects, but it's not that simple. While genetics may predispose someone to depression, there are a number of effective lifestyle factors over which we have control. Evaluation of the efficacy of withania somnifera (ashwagandha) root extract in patients with obsessive-compulsive disorder: a randomized double-blind placebo-controlled trial. Certain ingredients can influence the effectiveness of your antidepressants and how they affect your health. Celexa, on the other hand, is a selective serotonin reuptake inhibitor (SSRI). No major side effects or drug interactions were noted in this analysis. View abstract. PLoS One 2009;4:e6628. Nevertheless, there can be some interactions or side effects with anything, including natural supplements, which is why it is good to check in with a naturopathic doctor or another practitioner who is well-trained in drug-nutrient-herb interactions. If you are experiencing serious medical symptoms, please see the Peter Bongiorno is a naturopathic doctor and the author of Healing Depression: Integrated Naturopathic and Conventional Treatments. 2013;74(11):1076-83. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. O'Connor J, Lindsay K, Baker C, Kirby J, Hutchins A, Harris M. The impact of ashwagandha on stress, sleep quality, and food cravings in college students: quantitative analysis of a double-blind randomized control trial. Cancer Lett. 2023 eHealthMe.com. These medications may cause some risk when taken together. It is also not recommended to be used in pregnancy. View abstract. Sleep Med. But I'm not sure why you're taking the other things. can i take ashwagandha with citalopram. Holy basil is the best at lowering cortisol, in my experience, but it's also blood sugar lowering. View abstract. Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Monitor your blood pressure closely. View abstract. of signs you need emergency medical attention or call 911. Lexapro has active ingredients of escitalopram oxalate. Taking ashwagandha along with diabetes medications might cause blood sugar to drop too low. 2011;68(1):3-8. 8 Warning Signs of Depression You Shouldn't Ignore, Depression in Adults With a Chronic Physical Health Problem: Treatment and Management, How Vegans Can Get All Their Nutrients (Without Taking Supplements), Complementary Therapies in Medicine Journal, 15 Celebrities Who Struggle With Anxiety and Depression, Australian Journal of Herbal Medicine: "B Vitamins Enhance Antidepressant Response in Adults", Open Neurology Journal: "Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial", Journal of Psychiatry: "Adjunctive Nutraceuticals for Depression: A Systematic Review and Meta-Analyses", Mayo Clinic: "MAOIs and Diet: Is It Necessary to Restrict Tyramine? By using this Site you agree to the following, By using this Site you agree to the following. Ashwagandha is said to be non-toxic and potentially safe for the body. It concluded that this ayurvedic medicine can act as a neuroprotective agent and can help prevent dementia, especially in older adults. The use of the eHealthMe site and its content is at your own risk. There are a variety of vitamins and minerals that are essential for good health. View abstract. Make sure you ask your healthcare provider before using any medicinal agent with your antidepressant. Safer Tapering to End Antidepressant Treatment, Why Antidepressants and Probiotics Could Be a Potent Pairing. Malviya, N., Jain, S., Gupta, V. B., and Vyas, S. Recent studies on aphrodisiac herbs for the management of male sexual dysfunction--a review. Celexa is an antidepressant which is used to treat a variety of mental health conditions. Sud Khyati S, Thaker B. View abstract. In case of overdose, immediately take them to the hospital. Indian J Pharmacol. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Sometimes, these supplements are stand-alone products or multivitamins; in other cases, they are mixed in with healthy food products, like spirulina, chlorella or herbal products. Tumori 8-31-1994;80(4):306-308. Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. 1998;20(1):191-198. As for sex drive, people don't usually like to talk about this, but if you know what really turns you on you should be able to work around that. The phase Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? PLoS.One. Indian J Physiol Pharmacol. View abstract. While supplement and drug-induced serotonin syndrome poses a major risk for people taking SSRIs, other antidepressants can require stricter dietary changes. Yes. Therapeutic Research Faculty 2020. However, SSRIs don't work for everyone, and other antidepressants work via different pathways in your body. Being on Pristiq and Zyprexa has kept my depression in check, but I have low energy and no motivation to do anything. 2008;6:14. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. 2003;19(3):211-222. Moderate Interactions. One study indicated that toxic effects of this herb were seen in doses equal to or higher than 1750 mg. Celexa is an antidepressant which belongs to the class of selective serotonin reuptake inhibitors (SSRIs). 2016 Jun 1;173(6):575-87. Minimum recommended dosage of ashwagandha is round 300 to 500 mg. Celexa Oral. Am J Psychiatry. 2023 eHealthMe.com. If you take a benzo, of course, you should avoid these. 2013;2013:571420. The comparative effect of milk fortified with Aswagandha, Aswagandha and Punarnava in children - a double-blind study. View abstract. are not due to another medical condition, drug use, or discontinuation), Dyskinesia (abnormality or impairment of voluntary movement), Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures), Extrapyramidal disorder (involuntary muscle spasms in the face and neck), Fainting (loss of consciousness and postural tone), Flatulence (flatus expelled through the anus), Fluid retention (an abnormal accumulation of fluid in the blood), Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect), Foot deformity (functional disability of foot), Gallstones (stone formation by bile component), Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus), Gastrointestinal disorder (functional problems of gastrointestinal tract), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), General physical health deterioration (weak health status), Grand mal convulsion (a type of generalized seizure that affects the entire brain), Haematoma (collection of blood outside the blood vessels), Haemorrhoids (a swollen vein or group of veins in the region of the anus), Hallucination, auditory (perceiving sounds without auditory stimulus), Hallucinations (sensations that appear real but are created by your mind), Hallucination, visual (seeing things that aren't there), Heart palpitations (feelings or sensations that your heart is pounding or racing), Hyperhidrosis (abnormally increased sweating), Hyperkalemia (damage to or disease of the kidney), Hyperlipidaemia (presence of excess lipids in the blood), Hypoaesthesia (reduced sense of touch or sensation), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypotension (abnormally low blood pressure), Inappropriate antidiuretic hormone secretion, Intervertebral disc protrusion (spinal disc protrusion), Leukopenia (less number of white blood cells in blood), Malaise (a feeling of general discomfort or uneasiness), Mania (a state of abnormally elevated or irritable mood), Maternal drugs affecting foetus (chemical affecting the baby before birth taken by mother), Maternal exposure during pregnancy (use of substance during pregnancy), Melaena (the passage of black, tarry stools), Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability), Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition), Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation), Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body), Mobility decreased (ability to move is reduced), Mood swings (an extreme or rapid change in mood), Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness), Multi-organ failure (multisystem organ failure), Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. In fact, according to the book Depression in Adults With a Chronic Physical Health Problem: Treatment and Management, published in 2010 by the British Psychological Society, there are no specific vitamins contraindicated for consumption with antidepressants. WebTake citalopram once a day. Swelling or tenderness in different parts of the body. Examine.com says ashwaghanda stacks well with SSRI, it's in the "goes well with" category. J Ethnopharmacol 1991;33:91-5. The article then gets reviewed by a more senior editorial member. 8 people who take Lexapro and Ashwagandha together, and have interactions are studied. 2004;42(12):2015-2020. For example, ashwagandha (botanical name, Withania somnifera) is an herbal supplement found in anything from green smoothie mixes to root powder. J Ethnopharmacol 1999;64:91-3. Herpes spreads by oral, vaginal and anal sex. 2020;40(4):825-829. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. View abstract. Ashwagandha should not be used by everyone. View abstract. Take it with a meal. Malhotra, C. L., Mehta, V. L., Das, P. K., and Dhalla, N. S. Studies on Withania-ashwagandha, Kaul. According to the Mayo Clinic, all of these SSRIs work by blocking the reuptake of serotonin in the brain, which essentially makes serotonin more available. Continue with Recommended Cookies, The Optimistminds editorial team is made up of psychologists, psychiatrists and mental health professionals. Ireland PJ, Hardy T, Burt AD, Donnelly MC. Medicine (Baltimore). Gopukumar K, Thanawala S, Somepalli V, Rao TSS, Thamatam VB, Chauhan S. Efficacy and safety of ashwagandha root extract on cognitive functions in healthy, stressed adults: a randomized, double-blind, placebo-controlled study. Phytother Res 2022. 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